Surprising Recent suggestion - Some women’s bodies may be ‘sabotaging birth control hormones’

sabotaging birth control hormones


Contraceptives are used by people across our country. Birth control is generally taken to prevent pregnancy but a recent study suggests it may not be as effective in some women, for a surprising reason.

"Contraception is something that affects a very large portion of the population. And there are very few things that would explain why contraception didn't work"

What is contraception?

Contraception is the use of hormones or especially pregnancy prevention, devices or surgery to prevent a woman from becoming pregnant. It allows couples to choose if and when they want to have a baby or when they want to be parents.

Sabotaging birth control hormones

When a woman or girl gets pregnant while on the pill or other hormonal birth control that control or stop pregnancy, doctors often assume she didn't use the contraceptive properly. But a new study suggests that in some cases or now we say that in recent most of the women, a woman's genes may put her at risk for an unplanned pregnancy (surprising pregnancy or unwanted pregnancy) even while using hormonal birth control properly or using safety. That is why Troy Moore which is a Huntsville genetic scientist, says a recent study regarding birth control effectiveness stands out. It means some times birth control is out of control.

When you ingest a hormone you want it to release in a very controlled way.



In fact for this study the authors took out the variability of having to take it orally, explained Moore. "They looked at an implant so that it's a constant dosage within the body.”

The scientific author, Aaron Lazorwitz, focused in on a particular gene called ‘CYP3A7*1c’.
"What they found was some of these women, out of 350 women studied, 18 of them had a lower level of a hormone in their body, and they also had a particular set of changes in one gene," added Moore.
That gene is normally found in fetuses but switches off in most infants.

If we talk some other women, in some women, the gene never switches off and the CYP3A7 protein still generates in their body.

The authors say it breaks down the hormones used in birth control rendering it less effective or not working properly in some bodies.

"The birth control itself is 99 percent effective," explained Moore. "We don't know exactly the rate of variation(more or less) of this one particular gene but we should keep in mind that it is actually very rare that we know."

Moore says that this study could be one step in the right direction for improving and specializing preventative care.

Some work may take place right here in the Rocket City.

"We offer genetic testing and it was one of the things that caught my attention when I read this study. I thought, 'maybe we should think about developing a test for these particular genes so that women that have concerns about it could get tested,'" he said.
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Anna Schafer
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August 31, 2019 at 9:54 AM ×

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Anna Schafer
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August 31, 2019 at 9:54 AM ×

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